منابع مشابه
The conjugated steroids. IV. The hydrolysis of ketosteroid sulfates.
Specific hydrolysis of the separate groups of steroid conjugates appeared to offer the simplest technique for achieving the hydrolysis without chemical modification of the steroids (3-5). A partial solution to this problem was offered when it was found that steroid glucuronides could be hydrolyzed specifically by the use of /3-glucuronidase concentrates of either animal (Cohen (3)) or bacterial...
متن کاملSteroids of pregnant mares' urine. IV. Fractionation of the neutral steroids. Examination of some non-ketonic fractions.
Previous papers in this series (Klyne, Schachter & Marrian, 1948; Klyne, 1948; Paterson & Klyne, 1948) have described the isolation from pregnant mares' urine of 5a-pregn-16-en-3,B-ol-20-one, uranediol and 5a-pregnane-3,B-ol-20-one as their sulphuric acid esters. This paper describes the fractionation of the neutral steroids of pregnant mares' urine and the detailed examination of some non-keto...
متن کاملAnabolic steroids.
Athletes, like others, use recreational and lorillicit psychoactive drugs. However, many athletes also use drugs to enhance their training or performance, including an array of bizarre and exotic substances. Although the majority of these substances are not psychoactive, they may be abused by athletes. Some of these substances, such as anabolic steroids and human growth honnone, are referred to...
متن کاملAnabolic steroids.
The term "anabolic steroids" refers to testosterone derivatives that are used either clinically or by athletes for their anabolic properties. However, scientists have questioned the anabolic effects of testosterone and its derivatives in normal men for decades. Most scientists concluded that anabolic steroids do not increase muscle size or strength in people with normal gonadal function and hav...
متن کاملIgnoring steroids
A new study by Ito and colleagues on page 7 may help explain why patients with a severe lung disease called chronic obstructive pulmonary disease (COPD) fail to respond to steroid treatment. Ito and colleagues show that steroids require the enzyme HDAC2 (histone deacetylase 2) to block the inflammatory transcription factor NF-κB. In patients with COPD, HDAC2 activity is reduced, rendering cells...
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ژورنال
عنوان ژورنال: Nippon kagaku zassi
سال: 1949
ISSN: 0369-5387,2185-0917
DOI: 10.1246/nikkashi1948.70.303